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5th
INMED/TINS CONFERENCE
SEPTEMBER 9 - 12, 2006 LA
CIOTAT -
FRANCE
Physiogenic
and
pathogenic oscillations: the beauty and the beast
Neuronal networks generate a variety of oscillations and patterns that
are involved in sensory integrative processes as well as memory
processes. Thus, sensory biding is thought to involve the generation of
oscillations in different parts of the brain involved in various
sensory modalities that somehow help reconstructing the imageĀ.
Oscillations are also involved in a wide range of pathogenic patterns
and provide a signature of the neurological disorder. Thus, in
Parkinson disease, abnormal patterns are likely involved in akinetic
disorders and epilepsies are associated with high frequency
oscillations that in fact also operate to transform a naive
structure
to one that generate seizures on the principle that "seizures beget
seizure".
Using a wide range of recordings and preparations, imaging techniques
and mathematical models, we are beginning to understand how the machine
generate these patterns and which neuronal population plays a dominant
role in the generation of a given pattern. What is now needed is to
confront the various results and concepts and to generate an organised
model of the physiogenic patterns and the pathogenic ones: what are the
similarities and differences in terms of mechanisms, of generators
etc. We shall invite to the meeting experts in the clinical and
physiological, imaging and theoretical aspects of the question. We
expect the venue of students and senior researchers in neurology and
neurobiology as well as mathematics and modelling.
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